Wednesday, 7 December 2016

Key Analytical Challenges for Antibody Drug Conjugates

Key Analytical Challenges for Antibody Drug Conjugates 

Currently, there are more than 75 antibody drug conjugates (ADCs) in various stages of pre-clinical and clinical development. The combination of a targeted antibody coupled with a cytotoxic small-molecule drug (via  a flexible linker) makes for a lethal and specific oncologic drug product. However, an ADC is a heterogeneous cocktail of molecules with a range […]

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